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Cholesterol Management >> Side Effects of Statin Drugs >> Torcetrapib
Raising HDL Cholesterol with Torcetrapib May Also Raise Blood Pressure
© 2005 - Frank Mangano
Drug manufacturers are currently looking at the entire lower cholesterol picture as a new way to promote good heart health. Leading the efforts is Lipitor manufacturer, Pfizer who has recently introduced a new drug ingredient called torcetrapib. It has been shown in preliminary testing that began in 1999 to raise High Density Lipoprotein (HDL) – the good kind of cholesterol. The problem is that in an effort to raise HDL cholesterol, torcetrapib also seems to raise blood pressure. Production on a combination torcetrapib/atorvastatin drug began in June 2005 at Pfizer’s $90 million plant in Loughbeg, Ireland.
Higher doses of torcetrapib in clinical studies indicate that while trying to raise HDL cholesterol to prevent heart disease, users could simply be exchanging one condition for another. Elevated blood pressure can lead to stroke and heart attack. A clinical trial of 25,000 patients worldwide is part of the testing process of the final formulation.
Pfizer also intends that torcetrapib, used to raise HDL, work with the statin drug Lipitor which lowers LDL cholesterol. It would require double medication for those trying to balance their cholesterol levels. This combination of drugs would have to first seek FDA approval against the odds, since there are antitrust laws that prohibit two drugs from the same manufacturer requiring combined use in order to work. Proponents of the drug marriage say it should pass, because lowering the rate of heart disease should be the primary goal.
There are already many effective, all natural ways to raise HDL cholesterol without having to take two medications and without raising blood pressure in the process. A low cholesterol diet, exercise and the use of supplements, especially vitamin B3 (niacin) can raise HDL cholesterol and lower LDL cholesterol to create that perfect, heart healthy balance. It will also improve blood pressure readings if that is a concern. The complete, proven method is outlined in The 60 Day Prescription Free Cholesterol Cure.
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