Cholesterol Management >> Side Effects of Statin Drugs >> CETP
CETP Inhibitors Raise Good Cholesterol and Lower Cholesterol Overall
There are two ways to lower cholesterol levels. One is to reduce the amount of Low Density Lipoprotein (LDL), which is produced by the liver. The second way to lower overall cholesterol levels is to raise the High Density Lipoprotein (HDL), which is considered the good cholesterol. Higher levels of HDL have been found to cleanse the build up of cholesterol along artery walls. It is this HDL cholesterol that is most impacted by the use of drugs known as CETP Inhibitors.
CETP is a type of protein that enables the production of cholesterol. For those who need to lower cholesterol the drugs in this class do so by raising HDL cholesterol by as much as 100 percent. They can also lower LDL cholesterol a little, but work best in combination with the statin class of drugs designed to lower LDL cholesterol. CETP inhibitors, such as the drug known as torcetrapib, do little to lower LDL cholesterol on their own. Only a 5-10 percent decrease was found in LDL cholesterol when taking torcetrapib solo.
The objective in managing cholesterol is to have total cholesterol levels below 200 mg/dL. LDL cholesterol should be below 100 mg/dL and HDL cholesterol needs to be above 60 mg/dL. High cholesterol is the diagnosis when total cholesterol reaches 240 mg/dL or above. Each is a measurement of the milligrams of the fatty cholesterol per deciliter of blood.
CETP inhibitors generally do not have severe side effects. Usually a headache is the only side effect, but the drug is also really only effective in one small aspect of cholesterol management. Significantly raising HDL cholesterol can also be accomplished by a good exercise regimen.
Diet plays an important role in lowering LDL cholesterol. In order to avoid having to use a combination of drugs to lower cholesterol, you can participate in a diet and exercise program that will bring about life long results without the side effects. The plan is outlined in The 60 Day Prescription Free Cholesterol Cure.
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