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Cholesterol Management >> Side Effects of Statin Drugs >> Crestor Risk for Asians
Asians Beware: Crestor Carries Greater Risk in Lowering Cholesterol
Asians using Crestor to lower cholesterol need to be aware of the added dangers of side effects. Crestor is a class of cholesterol lowering drugs known as stain drugs that help prohibit the production of excessive cholesterol by the liver. When Asian patients had their blood tested, the amount of Crestor that remained in their systems was much higher than that of the average population on Crestor.
As a result of higher absorption of Crestor in Asians, the Food & Drug Administration (FDA) is warning that doctors should start Asian patients on the lowest dose possible to avoid serious side effects. These side effects include severe muscle soreness and weakness, which can indicate rhabdomyolysis – or kidney damage. The same warning is given to those with kidney disease or those who take cyclosporine to decrease the chances of rejection after a kidney, liver, or heart transplant.
The FDA recommends Asians begin with the lowest dose of Crestor currently available, which is 5 milligrams. The drug is prescribed in quantities as high as 40 milligrams. With higher doses, there is an increased risk of side effects. An insert developed by the FDA and the manufacturer of Crestor, Astra-Zenec Pharmaceuticals, is now placed in all prescriptions to warn patients of the risks. Because the risk of muscle damage is the same for all statin drugs as with Crestor, Asian patients and others should use caution with Lipitor, Zocor, Pravachol, and other popular cholesterol reducing drugs in this class.
To lower cholesterol without the risk of serious side effects, those with high cholesterol should begin by evaluating their diet and lifestyle. A low fat and low cholesterol diet should be the first step taken to lower cholesterol naturally. A proven effective plan can be found in The 60-Day Prescription Free Cholesterol Cure.
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