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Cholesterol Management >>Side Effects of Statin Drugs >> Paraoxonase
Enzyme Works with HDL for Lowering Cholesterol
An enzyme, paraoxonase or PON1, has been found to help the High Density Lipoprotein (HDL) cholesterol in lowering cholesterol overall. It does this by boosting the HDL’s ability to cleanse the arteries of a build up of Low Density Lipoprotein (LDL), which is the so-called bad cholesterol.
Paraoxonase is found in the blood in amounts determined by genetics. More importantly the activity levels of PON1 determine how well it works in lowering cholesterol and the chance of heart attacks or other heart related diseases. Recent studies have discovered that higher activity levels of PON1 mean there are higher HDL levels, and the quality of the work the HDL can do in lowering overall cholesterol is increased.
Those who are not genetically disposed to high activity levels of PON1 can help increase levels through exercise and a diet rich in antioxidants. Increased exercise has long been proven to increase HDL, but an increase in the enzyme PON1 is the reason behind the success. In one study, which evaluated a group of men aged 49-65 over a 15-year period, a 20 percent increase in activity of the PON1 enzyme cut the risk of heart attack by almost one-half. Studies on women have not yet been conducted, but the researchers hypothesize that increasing the activity of paraoxonase in woman will prove just as effective in lowering cholesterol.
Often drugs are used for lowering cholesterol. These work either by lowering levels of LDL cholesterol production by the liver and/or raising the HDL levels. The drugs are accompanied by side effects that range in severity from uncomfortable to life threatening. The fact that paraoxonase activity can be raised through diet and exercise is good news to those looking for ways to lowering cholesterol naturally. For more important information on lowering cholesterol without the use of drugs, you can get The 60-Day Prescription Free Cholesterol Cure.
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