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Cholesterol Management >> Lipoproteins >> Mannose Binding Lectin
Cholesterol Levels and Risk of Heart Disease Linked to Protein
A specific protein known as Mannose Binding Lectin (MBL) has been linked to an increased risk of heart disease that is also magnified by high cholesterol. Because high cholesterol can add to the hardening of the arteries brought about by low levels of MBL, the link has been the topic of a several studies involving MBL and cholesterol.
MBL is made by the liver in order to help stimulate the body’s immune system. When a virus or bacteria enter the body, the liver produces higher amounts of MBL. This then can either fight the pathogen or it can signal other areas of the immune system to do its job of fighting the invader. MBL usually acts as the first defense in stimulating the auto-immune system.
The link is that lower levels of MBL seem to coincide with higher incidents of heart attack from the development of atherosclerosis. Heart attack is more prevalent when there is inflammation of the arteries which causes them to narrow. The inflammation is reduced by a presence of higher levels of MBL. Cholesterol plays a role also in the ability of blood to flow freely through the arteries. When there is excessive amounts of cholesterol in the blood it clogs the passage way and narrows the artery opening.
Statin drugs that are used to combat high cholesterol also have anti-inflammatory properties. When someone is prescribed a drug such as Lipitor it also helps prevent atherosclerosis. However, all statin drugs used to manage cholesterol or reduce inflammation have side effects ranging from muscle soreness to complete kidney failure.
Cholesterol can be managed by diet and exercise. This will help the liver do its jobs of producing MBL and the appropriate cholesterol levels. To learn more, you can read The 60-Day Prescription Free Cholesterol Cure.
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